Isobutylzinc bromide
Isobutylzinc bromide
CAS: 126403-67-6
Molecular Formula: C4H9BrZn
Isobutylzinc bromide - Names and Identifiers
Isobutylzinc bromide - Physico-chemical Properties
| Molecular Formula | C4H9BrZn |
| Molar Mass | 202.41 |
| Density | 0.943g/mLat 25°C |
| Flash Point | 1°F |
| Water Solubility | Reacts with water. |
| Storage Condition | 2-8°C |
| Sensitive | Air Sensitive |
Isobutylzinc bromide - Risk and Safety
| Risk Codes | R14 - Reacts violently with water R19 - May form explosive peroxides R22 - Harmful if swallowed R36/37/38 - Irritating to eyes, respiratory system and skin. R40 - Limited evidence of a carcinogenic effect R36/37 - Irritating to eyes and respiratory system. R14/15 - R11 - Highly Flammable |
| Safety Description | S16 - Keep away from sources of ignition. S23 - Do not breathe vapour. S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing. S43 - In case of fire use ... (there follows the type of fire-fighting equipment to be used.) S36/37 - Wear suitable protective clothing and gloves. |
| UN IDs | UN 3399 4.3/PG 2 |
| WGK Germany | 1 |
| HS Code | 29319090 |
| Hazard Class | 4.3 |
Isobutylzinc bromide - Introduction
Isobutylzinc bromide(Isobutylzinc bromide) is an organic zinc compound with the chemical formula C4H9ZnBr. The following is a brief description of its nature, use, preparation and safety information:
Nature:
Isobutylzinc bromide is a colorless liquid with a special orange flavor. It is stable in air, but will slowly hydrolyze. It can be crystallized at low temperature.
Use:
1. Isobutylzinc bromide is often used as a reagent in organic synthesis. It is an important zinc-like reagent in organic synthesis and can react with various organic halides to generate corresponding compounds. For example, it can be used for coupling reactions of aromatic compounds, alkyl bromides, alcohols, and the like.
2. In addition, Isobutylzinc bromide can also be used in the field of organometallic chemistry.
Preparation Method:
Isobutylzinc bromide are typically prepared by reacting dimethyl zinc and a bromine source. The specific preparation method is as follows:
Under an inert atmosphere, dimethyl zinc is dissolved in an inert solvent such as anhydrous tetrahydrofuran (THF) or diethyl ether, and then a bromine source (such as bromoethane) is slowly added to the reaction. The resulting product is purified by distillation or crystallization to give the Isobutylzinc bromide.
Safety Information:
1. Isobutylzinc bromide has low toxicity, it is still necessary to pay attention to safe operation. When in use, should take appropriate protective measures, such as wearing protective gloves and glasses.
2. Since Isobutylzinc bromide can be hydrolyzed to produce harmful gases (hydrobromic acid), it should be operated in a well-ventilated place to avoid inhaling harmful gases.
3. Isobutylzinc bromide should be stored in a dry, dark place, away from fire and oxidant.
4. When handling Isobutylzinc bromide, follow local safe practices and chemical handling guidelines.
Nature:
Isobutylzinc bromide is a colorless liquid with a special orange flavor. It is stable in air, but will slowly hydrolyze. It can be crystallized at low temperature.
Use:
1. Isobutylzinc bromide is often used as a reagent in organic synthesis. It is an important zinc-like reagent in organic synthesis and can react with various organic halides to generate corresponding compounds. For example, it can be used for coupling reactions of aromatic compounds, alkyl bromides, alcohols, and the like.
2. In addition, Isobutylzinc bromide can also be used in the field of organometallic chemistry.
Preparation Method:
Isobutylzinc bromide are typically prepared by reacting dimethyl zinc and a bromine source. The specific preparation method is as follows:
Under an inert atmosphere, dimethyl zinc is dissolved in an inert solvent such as anhydrous tetrahydrofuran (THF) or diethyl ether, and then a bromine source (such as bromoethane) is slowly added to the reaction. The resulting product is purified by distillation or crystallization to give the Isobutylzinc bromide.
Safety Information:
1. Isobutylzinc bromide has low toxicity, it is still necessary to pay attention to safe operation. When in use, should take appropriate protective measures, such as wearing protective gloves and glasses.
2. Since Isobutylzinc bromide can be hydrolyzed to produce harmful gases (hydrobromic acid), it should be operated in a well-ventilated place to avoid inhaling harmful gases.
3. Isobutylzinc bromide should be stored in a dry, dark place, away from fire and oxidant.
4. When handling Isobutylzinc bromide, follow local safe practices and chemical handling guidelines.
Last Update：2024-04-10 22:29:15
